Two parents with children with Down syndrome meet at a clinic.

Two parents with children with Down syndrome meet at a clinic. The Walters know that their son has trisomy 21. The Benders, however, have two affected children, and Mrs. Bender has had three spontaneous abortions. Explain why the Benders probably should be more concerned about future reproductive problems than the Walters.

In summary, the Benders’ situation suggests a higher likelihood of genetic factors influencing their reproductive outcomes, making them more prone to future challenges compared to the Walters, who have only one child with trisomy 21 without additional reproductive complications.